President Orders ‘Genesis Mission’ to Unleash AI-Driven Science
By the authority vested in me as President by the Constitution and the laws of the United States of America, it is hereby ordered:
Section 1. Purpose. From the founding of our Republic, scientific discovery and technological innovation have driven American progress and prosperity. Today, America is in a race for global technology dominance in the development of artificial intelligence (AI), an important frontier of scientific discovery and economic growth.
The Administration points to prior steps, including issuing Executive Orders and implementing America’s AI Action Plan, as part of a larger push to invest in AI-enabled science to accelerate scientific advancement. This moment is presented as an inflection point that demands a national effort on the scale of the Manhattan Project, which helped establish the Department of Energy and the national laboratories. The comparison is meant to signal urgency and large-scale coordination across government, academia, and industry.
Editor’s note: America is in race with itself, but declared with upmost urgency. The phrase “accelerate scientific advancement” refers to “accelerationism”, which is part of the Dark Enlightenment. Marc Andreessen wrote in his Techno-Optimist Manifesto: “We believe in accelerationism – the conscious and deliberate propulsion of technological development – to ensure the fulfillment of the Law of Accelerating Returns. To ensure the techno-capital upward spiral continues forever.” – End Editor’s note.
This order launches the “Genesis Mission” as a dedicated, coordinated national effort to unleash a new age of AI-accelerated innovation and discovery that can solve the most challenging problems of this century. The stated goal is to build an integrated AI platform that leverages Federal scientific datasets—the world’s largest such collection built over decades—to train scientific foundation models and deploy AI agents. Those agents are intended to propose and test hypotheses, automate research workflows, and speed breakthroughs in fields from energy to medicine.
The Genesis Mission is designed to marshal the Nation’s R&D capacity by combining work at national laboratories with private-sector innovation and university research. It explicitly mentions production plants, data repositories, and national security sites as parts of the ecosystem to be tapped. A clear line is drawn between accelerating discovery and strengthening national security along with economic competitiveness.
Officials describe leveraging decades of progress in semiconductors and high-performance computing to power the effort, with a focus on multiplying the return on taxpayer investments in research and development. The plan emphasizes workforce productivity gains and claims potential to secure energy dominance through targeted AI applications. This is framed as a way to extend America’s technological and strategic leadership in a world where AI capabilities translate directly into geopolitical and economic power.
The order stresses coordination: federal datasets, national labs, universities, and companies are all meant to operate together under the Genesis Mission umbrella. It calls for an integrated platform and shared tools to prevent duplication and speed adoption of breakthroughs. The approach assumes centralized effort will deliver faster, more reliable outcomes than fragmented, siloed projects.
For skeptics, the use of large federal datasets and centralized platforms raises questions about access, ownership, and oversight of research outputs. There are also concerns about the pace of deployment and the ethical guardrails around AI agents that can design experiments and influence technical choices. Those governance and transparency issues will shape how the program is received across the research community and the public.
Politically, this initiative is pitched as a bold Republican-friendly argument for national investment in technology to preserve American competitiveness and security. The rhetoric leans on industrial mobilization and public-private partnership rather than regulatory restraint, positioning federal leadership as the catalyst to win the global AI competition. The Genesis Mission is presented not as a policy tweak but as a high-urgency national campaign to convert scientific potential into strategic advantage.